Fantasy Football Week 6 QB Start and Sit Guide for Optimal Lineup Decisions

Your Go-To Guide for Fantasy Football Matchups: Start ‘Em, Sit ‘Em for Week 6

As the 2025 NFL season heats up, fantasy football enthusiasts prepare to make critical lineup decisions based on optimal matchups. This week’s “Start ‘Em, Sit ‘Em” focuses on players who may defy or disappoint expectations in a PPR scoring system. While star players like Josh Allen and Ja’Marr Chase are household names, this column highlights lesser-known talents who could swing your fantasy outcome.

Top Quarterback Picks for Week 6

When assessing quarterback performances, consider matchups carefully. Below are the quarterbacks to start based on favorable conditions:

• Justin Herbert at Dolphins (1 p.m. ET, CBS): Despite an underwhelming three-week performance, Herbert faces a Dolphins defense that has given up over 23 fantasy points to four quarterbacks in five games.
• Drake Maye at Saints (1 p.m. ET, CBS): After a slight setback against the Bills, Maye is poised for a rebound against a Saints defense allowing over 18 points to multiple quarterbacks.
• Jordan Love vs. Bengals (4:25 p.m. ET, CBS): Love has recorded 20-plus points in two of his last three games, facing a Bengals team that has recently struggled against opposing quarterbacks.
• Bo Nix at Jets (9:30 a.m. ET, NFL Network): Nix has been impressive lately, and he can continue this trend against a Jets defense that has leaked fantasy points to quarterbacks.
• Matthew Stafford at Ravens (1 p.m. ET, Fox): Stafford’s recent performances feature six touchdown passes and a robust fantasy output, putting him in a favorable position this week.

Other Notable Starts

• Bryce Young vs. Cowboys (1 p.m. ET, Fox)
• Mac Jones at Buccaneers (4:25 p.m. ET, CBS)
• Caleb Williams at Commanders (Mon. 8:15 p.m. ET, ABC)

Quarterbacks to Sit This Week

While some players should be in your lineup, others are better left on the bench. Consider the following quarterbacks for your “Sit ‘Em” list:

• Justin Fields vs. Broncos (9:30 a.m. ET, NFL Network): Fields performed well last week but faces a Broncos defense allowing just 13 points per game to quarterbacks.
• Jared Goff at Chiefs (8:20 p.m. ET, NBC): Despite a solid outing last week, Goff is up against a Chiefs defense that has stifled quarterback scoring this season.
• Tua Tagovailoa vs. Chargers (1 p.m. ET, CBS): After a high-scoring game last week, Tagovailoa struggles against a Chargers defense which has kept quarterback scores low on the road.
• Aaron Rodgers vs. Browns (1 p.m. ET, CBS): The Browns defense is formidable, limiting quarterback scoring, thus making Rodgers a risky start this week.
• Sam Darnold at Jaguars (1 p.m. ET, Fox): Following a standout game, Darnold may find it challenging against a Jaguars defense that limits quarterback scoring significantly.

Conclusion

Each fantasy matchup presents unique challenges and opportunities. Ensure your lineup reflects insightful strategies based on current performances and upcoming matchups. For continuous updates, refer to Emegypt’s weekly player rankings throughout the season to enhance your fantasy football journey.