2025 NBA DFS Top FanDuel and DraftKings Picks and Strategies for Tuesday October 21 from a Daily Fantasy Expert

The 2025-26 NBA season kicks off on Tuesday, October 21, featuring pivotal matchups. NBA Opening Night will showcase a thrilling game between the Houston Rockets and the Oklahoma City Thunder, highlighting Kevin Durant’s debut with the Rockets against Shai Gilgeous-Alexander. The evening will also include a marquee battle between Stephen Curry’s Golden State Warriors and Luka Doncic’s Los Angeles Lakers.
NBA DFS Top FanDuel and DraftKings Picks for October 21
As NBA daily fantasy sports (DFS) players prepare their lineups for Opening Night, expert insight is crucial. Mike McClure, a recognized DFS professional with career winnings exceeding $2 million, provides valuable strategies. He utilizes a sophisticated prediction model that simulates games 10,000 times, analyzing crucial factors such as matchups and player injuries.
Key Player Picks
- Luka Doncic: Priced at $11,000 on DraftKings and $11,700 on FanDuel, Doncic is poised to post significant numbers.
- Isaiah Hartenstein: The Thunder’s center, available for $5,400 on DraftKings and $5,800 on FanDuel, had a standout season. He averaged 11.2 points, 10.7 rebounds, 3.8 assists, and 1.1 blocks, shooting 58.1% from the field.
Optimal Lineup Strategies
McClure emphasizes the importance of including both star players and underrated assets in your lineup. His strategies can significantly impact the outcome of tournaments and cash games.
Before submitting your NBA DFS lineups on Emegypt, take a moment to explore these key insights. Utilizing expert advice and careful player selections can enhance your chances of success this NBA season.